Miles to Smile

  

  M.S. Saravana Kumar , Mohammad Akheel

 Abstract

Achieving an aesthetic smile through the construction of 20 sound units of Fixed Partial Dentures (FPD) on endodontically treated teeth with post and core, as well as performing atraumatic extractions in a limited period of time, poses a great challenge to dental practitioners. This clinical report focuses on the prosthetic rehabilitation of a 44-year-old patient who came from South Africa seeking to replace his lost smile. ...Read More >>

 Granular Cell Tumor of the Tongue (Abrikossoff'stumor)

  

  J. Dinakar , M. S. Senthil Kumar , Shiju Mathew Jacob

 Abstract

Granular Cell tumor (GCT), also known as Abrikossoff's tumor, is a relatively uncommon benign neoplasm that affects the tongue. It typically presents as a solitary, asymptomatic, sessile nodule on the dorsum of the tongue. The histogenesis of this tumor is uncertain, and it's unclear whether it originates from neural or muscular tissue. In this report, we describe the case of a 29-year-old male patient who presented with a nodular swelling on the tip of the dorsal surface of his tongue. Initially diagnosed as a traumatic fibroma, a biopsy revealed that the lesion was, in fact, a granular cell tumor. ...Read More >>

 Giant Recurrent Pyogenic Granuloma: A Case Report

  

  Sivakumar P. , Sudhakar , NadeemJeddy , Shankaranarayanan

 Abstract

Pyogenic Granuloma (PG) is a relatively common, rapidly enlarging, non-neoplastic, reactive oral lesion that frequently occurs in the gingiva, ranging in size from a few millimeters to several centimeters. Smaller lesions are usually asymptomatic, whereas larger ones may cause various discomforts to the patient, such as hindrance in speech, inability to close the mouth, and profuse bleeding. In this report, we present the case of a 52-year-old woman with a huge pyogenic granuloma that resulted in an inability to close her mouth. Despite the excision of the lesion, it recurred after one month, with no evidence of any local irritational factors. ...Read More >>

 Diabetic Periodontitis and Advanced Glycation End Products (AGE)

  

  R. Mythili , V. Krishnan , Rajeev Chandran K.

 Abstract

The role of chronic hyperglycemia in the development of diabetic complications has been clearly established by intervention studies. However, the biochemical or cellular links between elevated blood glucose levels and periodontal lesions remain incompletely understood. This review focuses on the consequences of hyperglycemia on the formation of advanced glycation end-products (AGES) and on the role of AGES and their specific receptors (RAGE) in periodontal lesions. AGES are formed during the Maillard reaction by the binding of aldoses on free NH2 groups of proteins, which, after a cascade of molecular rearrangements, result in molecules of brown color and specific fluorescence. Experimental studies have indicated that the binding of AGES to RAGE activates cells, particularly monocytes and endothelial cells. Activated endothelial cells produce cytokines and express adhesion molecules and tissue factor. The role of AGES in increased oxidative stress and in the functional alterations in vascular tone control observed in diabetes, partly related to a reduction in nitric oxide, is also discussed. The microvascular lesions induced by experimental diabetes in animals are prevented by RAGE, which hinders AGES-RAGE interaction, prevents hyperpermeability and vascular lesions. These data suggest a central role of AGES and RAGE in the development of chronic complications of diabetes, especially periodontitis. The administration of recombinant inhibitors of AGES formation, such as aminoguanidine, in diabetic animals supports this hypothesis. ...Read More >>

 A Study on Evaluation of Centre of Resistance of Maxillary Central Incisor During Intrusion- A Finite Element Study

  

  Aruna J. , Uma Shankar , Rajagopal

 Abstract

The aim of this study is to evaluate the center of resistance of the maxillary central incisor during intrusion. The study employed the following steps: pre-processing, which involved creating a geometric model, mesh generation, and boundary conditions; and post-processing, which involved analyzing tooth movement and determining the center of resistance. The results showed that the center of resistance for the maxillary central incisors was measured to be 6.67 mm and exhibited maximum resistance to movement from the applied force. This study provides a sound mechanical method of analysis that is sufficient to provide insight into the interactions between orthodontic forces and dental tissues, and it is reliable. Clinically, this study can be used to precisely locate the center of resistance in single-rooted teeth during orthodontic treatment. ...Read More >>